Surgery for early-stage small cell lung cancer: is it worth it?

Melissa A. L. Vyfhuis, Pranshu Mohindra, Charles B. Simone II


We commend Yang et al. on their recent population-based analysis entitled “Long-term Survival After Surgery Compared with Concurrent Chemoradiation for Node-negative Small Cell Lung Cancer” that was recently published in Annals of Surgery (1). National Comprehensive Cancer Network (NCCN) guidelines state that in patients who are medically operable, surgical resection and adjuvant chemotherapy (± radiotherapy) remain standard of care for those with early stage, node-negative small cell lung cancer (SCLC) (2).