Article Abstract

Investigating thymic epithelial tumor, the “source” of autoimmunity and immunodeficiency: a lesson from ITMIGRD

Authors: Liliana Montella, Margaret Ottaviano, Giovannella Palmieri


The International Thymic Malignancy Interest Group Retrospective database (ITMIGRD) is a precious source of data concerning thymic epithelial tumors (TETs), one of the rarest adult malignancies. Thymic neoplasms are a strange type of cancer as concerns biological and clinical behavior and the peculiar association with paraneoplastic syndromes, either autoimmune diseases or clinical manifestations of immunodeficiency. The identification of these immunological disorders is important for physicians that treat these patients.