Paraneoplastic autoimmune diseases in patients with thymic malignancies: a favorable, but not independent, prognostic factor

Paola Cavalcante, Renato Mantegazza, Pia Bernasconi


Thymomas and thymic carcinomas are rare epithelial tumors of thymus (TETs) associated with paraneoplastic autoimmune (PN/AI) disorders, including myasthenia gravis (MG), pure red cell aplasia, hypogammaglobulinemia, encephalitis, and acquired neuromyotonia (1,2). Patients affected by these disorders are usually screened for thymoma at diagnosis, and they frequently improve with thymoma treatment (2).